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7-Substituted Pyrrolo[2,3-d]pyrimidines For The Synthesis Of New 1-deazapyrimido[1,2,3-cd]purines

Lyubov Muzychka, Iryna Yaremchuk, Iryna Yaremchuk, Oleg Smolii

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Few examples of new heterocyclic 1-deazapyrimido[1,2,3-cd]purine derivatives were synthesized by intramolecular cyclization of methyl 7-(oxiran-2-ylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylates. The latter were obtained by iodolactonization of 7-allylpyrrolo[2,3-d]pyrimidine-6-carboxylic acids.