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Vitamin D As A Factor For Improving The Quality Of Life In Women After 50 Years (literature Review)

Tatyana Yu. Pestrikova, Elena A. Yurasova, Tatyana P. Knyazeva

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Relevance. Public health is one of the key factors in the development of the economy and at the same time an objective indicator of quality of life. Currently, the number of women over 50 years old is progressively increasing, and their growing social inclusion will determine the desire for active and healthy longevity. In this regard, the public health policy in the country should follow the path of increasingly large-scale financing of projects of a healthy lifestyle, not concentrating expenses only on medical care. Aim. Analysis of literature on the feasibility of using vitamin D as a factor that improves the quality of life of women in the perimenopausal period and in menopause. Materials and methods. To write this review, we searched for domestic and foreign publications in Russian and international search engines (PubMed, eLIBRARY, etc.) over the past 20 years. The review included articles from peer-reviewed literature. Results. The review outlines a wide range of biological properties of vitamin D involved in the regulation of many important physiological functions. The negative effect of vitamin D deficiency is presented not only on the development of cancer, cardiovascular diseases, but also on the increase in the severity of menopausal syndrome. It has been established that the use of colecalciferol (vitamin D3) in combination with menopausal hormone therapy contributes to the normalization of carbohydrate, lipid and calcium phosphorus metabolism, improves the neuropsychic state of patients, which makes it possible to actively use colecalciferol in routine clinical practice in menopausal syndrome. Conclusions. Numerous positive effects of colecalciferol (vitamin D3) allow the use of the drug as a means to increase social adaptation, and, consequently, improve the quality of life.