Online citations, reference lists, and bibliographies.
← Back to Search

Experimental Vasospasm, Acute And Chronic, Due To Blood In The Subarachnoid Space.

F. Echlin
Published 1971 · Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
Share
✓ This investigation on monkeys provides arteriographic and other evidence that blood, in the absence of evident mechanical stimulation or injury to intradural arteries, will, when injected into the anterior cervical subarachnoid space through a catheter, consistently cause acute and chronic vasospasm of the intradural arteries, presumably where they are contacted by blood. Evidence indicates that vasoconstrictor agents or factors in fresh blood cause the vasospasm, since similar subarachnoid injection of saline or clear serum did not cause vasoconstriction. Other circumstances involving mechanical or other factors, such as vessel injury, may contribute to the length and severity of the vasospasm, but whether they have an etiological role needs further study.
This paper references
10.1136/jnnp.27.5.440
Death due to cerebral vasospasm
R. Buckle (1964)
A method of introducing blood into the subarachnoid space in the region of the circle of Willis in dogs.
W. Lougheed (1961)
10.3171/JNS.1964.21.9.0769
SUBARACHNOID HEMORRHAGE--FACTORS IN PROGNOSIS AND MANAGEMENT.
S. A. Stornelli (1964)
[Arterial spasm of the internal carotid due to a ruptured aneurysm of the vertebro-basilar system (apropos of 2 cases)].
G. Allègre (1963)
Aneurysms and arteriovenous anomalies of the brain : diagnosis and treatment
J. Pool (1965)
10.3171/JNS.1968.29.2.0121
Intracranial arterial spasm: a clinical analysis.
R. Wilkins (1968)
Fibrinolytic activity of the spinal fluid and meninges.
J. Porter (1966)
10.1097/00004424-196607000-00006
Spasm of Basilar and Vertebral Arteries Caused by Experimental Subarachnoid Hemorrhage
T. Newton (1966)
Cerebral vascular spasm : adrenergic blockade and catecholamine morphology
Fraser RAR (1970)
Cerebral arterial spasm. A short review.
Potter Jm (1961)
10.1136/bmj.1.4965.473
Surgery in Spontaneous Subarachnoid Haemorrhage
V. Logue (1956)
10.1001/ARCHNEUR.1964.00460240100013
INTRACRANIAL ANEURYSM RUPTURE, VASOSPASM, AND INFARCTION.
S. Schneck (1964)
10.1212/WNL.16.5.482
The role of circulating substances in intracranial arterial spasm
R. Wilkins (1966)
10.3171/JNS.1951.8.6.0660
Arteriographic demonstration of spasm of the intracranial arteries, with special reference to saccular arterial aneurysms.
A. Ecker (1951)
10.1001/ARCHNEURPSYC.1942.02290010087007
VASOSPASM AND FOCAL CEREBRAL ISCHEMIA: AN EXPERIMENTAL STUDY
F. Echlin (1942)
10.1212/WNL.18.11.1056
Prolonged cerebral vasospasm in experimental subarachnoid hemorrhage
B. Landau (1968)
10.3171/JNS.1968.29.4.0357
Prolonged experimental cerebral vasospasm.
F. Simeone (1968)
10.3171/JNS.1968.29.4.0331
Cerebral Arterial Spasm
J. Kapp (1968)
10.3171/JNS.1965.22.1.0021
RUPTURED INTRACRANIAL ANEURYSMS--THE ROLE OF ARTERIAL SPASM.
J. M. Allcock (1965)
10.1080/00325481.1954.11711615
The hemorrhagic disorders.
Sturgis Cc (1947)
10.1001/ARCHNEURPSYC.1932.02230130036003
INTRACEREBRAL VASCULAR NERVES
W. Penfield (1932)
10.3171/JNS.1961.18.6.0760
Manipulation Hemiplegia: An Untoward Complication in the Surgery of Focal Epilepsy
W. Penfield (1961)
Le spasme des art ~ res du cercle de Willis au cours des h 6 morragies traumatiques ou an 6 vrismales
RJ Vilato (1964)
10.3171/jns.1967.27.6.0490
Experimental studies of intracranial arterial spasm using aortic strip assays.
R. Wilkins (1967)
The relief of cerebral vasospasm by topically applied ethylene diamine tetra - acetic acid ( EDTA )
JL Pool (1969)
10.1016/S0140-6736(54)91821-8
The pathogenesis of hypertensive encephalopathy and its relation to the malignant phase of hypertension; experimental evidence from the hypertensive rat.
F. Byrom (1954)
10.1152/AJPLEGACY.1944.142.1.12
A STUDY OF THE SUBSTANCES IN BLOOD SERUM AND PLATELETS WHICH STIMULATE SMOOTH MUSCLE
M. Zucker (1944)
Spasme artrrial de la carotide interne dfi ~t un anrvrysme rompu du syst~me vertebro-basilaire (~ propos de 2 cas.) Neurochirurgie
G Allgre (1963)
[Images of spasm in intracranial aneurysms].
C. Gros (1953)
10.1093/BRAIN/48.1.43
MICROSCOPICAL OBSERVATIONS ON THE CIRCULATION OF THE BLOOD IN THE CEREBRAL CORTEX
H. Florey (1925)
10.1016/0002-9149(63)90033-X
Cerebral angiospasm. A cause of the cerebral stroke.
E. Corday (1963)
13 ber die Gefassspasmer ~ bei frisch rupturierten sackformigen Aneurys - men der Hirnarterien
W Walter (1962)
perimental vasospasm : induction , pharmacology , and catecholamine morphology in the laboratory animal
BM Stein (1962)
10.1093/BRAIN/61.2.221
VASOMOTOR CONTROL OF CEREBRAL VESSELS
H. S. Forbes (1938)
10.1253/JCJ.27.277
Effect of angiotensin on cerebral circulation in unanesthetized rabbit.
M. Ikeda (1963)
Arterial spasm in subarachnoid haemorrhage : mechanical considerations
E Kagstrom (1958)
Cerebral arterial spasm. 1. Evaluation of experimental variables affecting the diameteor of the exposed basilar artery.
J. Kapp (1968)
10.3171/JNS.1970.33.3.0260
Intracranial arterial spasm in the dog. A chronic experimental model.
R. Wilkins (1970)
10.1212/WNL.11.3.190
Cerebrovascular effects of topically applied serotonin in the cat
R. Raynor (1961)
The management of ruptured intracranial aneurysm.
Gillingham Fj (1958)
10.3171/JNS.1968.28.1.0001
The biphasic response of cerebral vasospasm in experimental subarachnoid hemorrhage.
B. Brawley (1968)
10.3181/00379727-113-28306
Serotonin and Histamine
W. K. O'steen (1963)
10.1136/jnnp.27.3.198
Demonstration of substances capable of contracting smooth muscle in the haematoma fluid from certain cases of ruptured cerebral aneurysm
M. Buckell (1964)
10.1007/BF00242653
Der cerebrale Arteriospasmus
E. Herrmann (2004)
10.1001/ARCHNEUR.1959.03840010040005
Cerebral vasospasm in angiography for intracranial aneurysms. Incidence and significance in one hundred consecutive angiograms.
T. Fletcher (1959)
10.1001/ARCHNEURPSYC.1951.02320070040002
Occlusion of the middle cerebral artery; an experimental study.
J. Harvey (1951)
10.3171/JNS.1953.10.4.0404
The treatment of aneurysms of the circle of Willis.
G. Norlén (1953)
10.1136/bmj.2.5191.12
Brain, Movement and Time*
N. Dott (1960)
10.1177/028418516300100219
Distribution of Spasm in the Intracranial Arteries after Subarachnoid Haemorrhage
G. Boulay (1963)
10.1097/00005792-194102000-00001
A CLINICAL AND PATHOLOGICAL STUDY OF SUBARACHNOID AND INTRACEREBRAL HAEMORRHAGE CAUSED BERRY ANEURYSMS
J. Richardson (1941)
10.1097/00004424-196811000-00004
Cerebral vasospasm induced by subarachnoid blood and serotonin. An angiographic study.
R. Chow (1968)
10.1177/02841851660050P108
Arterial Spasm in Subarachnoid Haemorrhage
J. M. Allcock (1966)
10.3171/JNS.1968.29.4.0350
Cerebral arterial spasm. 3. Partial purification and characterization of a spasmogenic substance in feline platelets.
J. Kapp (1968)
Surgery in spontaneous subarachnoid haemorrhage; operative treatment of aneurysms on the anterior cerebral and anterior communicating artery.
V. Logue (1956)
10.3171/JNS.1961.18.6.0843
Segmental cerebral arterial constriction associated with pheochromocytoma: report of a case with arteriograms.
F. Armstrong (1961)
The management of ruptured intracranial aneurysm.
F. J. Gillingham (1958)
10.1001/ARCHNEUR.1965.00470060051004
Influence of human cerebrospinal fluid on blood coagulation in vitro.
D. Devivo (1965)
10.1093/NEUROSURGERY/15.CN_SUPPL_1.133
Current concepts in the etiology and treatment of vasospasm.
F. Echlin (1968)
10.3171/JNS.1963.20.2.0094
PREVENTION OF SEROTONIN-PRODUCED CEREBRAL VASOSPASM: AN EVALUATION OF BLOCKING AGENTS.
R. Raynor (1963)
10.1001/ARCHNEURPSYC.1934.02250110003001
CEREBRAL CIRCULATION: XXXII. EFFECT OF STIMULATION OF THE SYMPATHETIC NERVE ON THE PIAL VESSELS IN THE ISOLATED HEAD
J. Pool (1934)
10.3171/JNS.1958.15.1.0004
Hypothermia in the surgical treatment of ruptured in tracranial aneurysms.
E. H. Botterell (1958)
Clinical and experimental spasm of the cerebral vessels
J Kapp (1969)
Der cerebrale Arterio - spasmus . Kasuistischer und radiologischer Beitrag zur Frage nach der Existenz von Spasmen der Hirnarterien unter ihrer Bedeutung fur die Genese des ischamischen Insults
WE Hunt (1963)
Observations on distension and contraction of cerebral blood vessels.
E. S. Gurdjian (1959)
10.3171/JNS.1960.17.1.0090
Local spasm in cerebral arteries.
R. Lende (1960)
10.3171/JNS.1951.8.1.0075
Specific treatment of intracranial aneurysms; experiences with 143 surgically treated patients.
J. Poppen (1951)
10.1016/S0022-4804(61)80028-0
The effects of normal cerebrospinal fluid on blood clotting and fibroblast growth.
R. Wilkins (1961)
Vasospasm , acute and recurrent , due to experimental subarachnoid hemorrhage
FA Echlin (1969)
Les images de spasme dans les anrvrismes intracraniens
C Gros
10.3171/JNS.1962.19.12.1023
Angiographic studies of experimental intracranial hypertension.
W. Hunt (1962)
10.1001/JAMA.1958.02990300025005
Cerebral vasospasm; clinical and experimental evidence.
J. Pool (1958)



This paper is referenced by
10.1155/2013/615154
Aneurysmal Subarachnoid Hemorrhage Models: Do They Need a Fix?
F. Sehba (2013)
10.3171/2008.8.JNS08591
Acute vasoconstriction: decrease and recovery of cerebral blood flow after various intensities of experimental subarachnoid hemorrhage in rats.
T. Westermaier (2009)
10.1076/noph.28.1.35.17341
Wyburn-Mason syndrome. Case report of unusual ipsilateral hemiparesis following subarachnoid hemorrhage
W. Drozdowski (2004)
10.1177/159101990000600203
Timing of ICAM-I Expression in a Canine Model of Post-Haemorrhagic Cerebral Vasospasm
T. Abruzzo (2000)
10.1161/01.STR.8.6.702
Experimental Cerebral Vasospasm After Subarachnoid Hemorrhage Development and Degree of Vasospasm
S. Endo (1977)
10.3171/JNS.1974.41.2.0177
Experimental intracerebral hematoma. Reduction of oxygen tension in brain and cerebrospinal fluid.
B. Sussman (1974)
10.1007/978-3-7091-0356-2_4
Effect of a free radical scavenger, edaravone, on free radical reactions: related signal transduction and cerebral vasospasm in the rabbit subarachnoid hemorrhage model.
Akira Munakata (2011)
10.1038/jcbfm.1984.68
Erythrocyte Extracts Enhance Neurogenic Vasoconstriction of Dog Cerebral Arteries in vitro
T. J. Lee (1984)
10.1016/j.jns.2018.11.007
Acute reaction of arterial blood vessels after experimental subarachnoid hemorrhage – An in vivo microscopic study
T. Westermaier (2019)
10.1111/j.1476-5381.1978.tb09754.x
MODELS FOR INVESTIGATING THE AETIOLOGY OF CEREBRAL ARTERIAL SPASM: COMPARATIVE RESPONSES OF THE HUMAN BASILAR ARTERY WITH RAT COLON, ANOCOCCYGEUS, STOMACH FUNDUS, AND AORTA AND GUINEA‐PIG ILEUM AND COLON
D. Boullin (1978)
10.1259/0007-1285-54-643-572
Vascular anatomy in the suboccipital region and lateral cervical puncture.
T. C. Cox (1981)
10.1161/01.STR.14.2.240
The angiopathy of subarachnoid hemorrhage: angiographic and morphologic correlates.
R. Smith (1983)
10.3171/JNS.1973.39.5.0629
Side effects of spasmolytic agents in the monkey. Intracisternal phenoxybenzamine and phentolamine.
A. N. Martins (1973)
10.1007/BF02255539
Acute Cerebral Artery Constriction in the Spontaneously Hypertensive Rat following Blood and Plasma Administration into the Subarachnoid Space.
C.G. Acuff (1996)
10.3171/JNS.1974.40.4.0473
The production of intracranial vascular spasm by hypothalamic extract.
J. Wilson (1974)
10.1076/apab.109.2.154.4275
Effects of Interrupted and Uninterrupted Occlusion of the Basilar Artery on Cerebral Blood Flow, and on Neurological and Histological Outcome in Rats with Subarachnoid Hemorrhage
T. Alkan (2001)
10.1179/174313209X382412
Experimental models of subarachnoid hemorrhage for studies of cerebral vasospasm
E. Titova (2009)
10.3171/JNS.1974.40.4.0433
Cerebral arterial spasm.
G. Allen (1985)
10.1161/01.STR.13.4.473
Angiographic study of vasospasm following subarachnoid hemorrhage in monkeys.
S. Peerless (1982)
10.1016/0090-3019(92)90185-P
Biphasic constriction of rabbit basilar artery following experimental subarachnoid hemorrhage: a morphometric study.
H. Johshita (1992)
10.2176/nmc.17pt2.47
Experimental Cerebral Vasospasm after Subarachnoid Hemorrhage
S. Endo (1977)
10.3171/JNS.1979.50.2.0158
Experimental assessment of phenoxybenzamine in cerebral vasospasm.
R. P. White (1979)
10.1161/01.STR.8.6.707
Blood Recirculation and Pharmacological Responsiveness of the Cerebral Vasculature Following Prolonged Ischemia of Cat Brain
S. Takagi (1977)
10.1161/01.STR.10.4.375
Role of Adrenergic Nerves in Blood-Induced Cerebral Vasospasm
F. A. Simeone (1979)
Possible role of the erythrocyte prolonged cerebral vasospasm in causing
N. Ozaki (1979)
10.1016/0304-3940(90)90781-4
Erythrocytes suppress calcitonin gene-related peptide- and vasoactive intestinal polypeptide-like immunoreactivities in cerebrovascular nerve fibers after subarachnoid hemorrhage
K. Nozaki (1990)
10.3171/JNS.1987.66.3.0431
Monoaminergic responses to spinal trauma. Participation of serotonin in posttraumatic progression of neural damage.
S. Salzman (1987)
10.3109/02688691003746274
Standard intracranial in vivo animal models of delayed cerebral vasospasm
S. Marbacher (2010)
10.1227/01.NEU.0000338067.83059.EB
EFFECT OF A FREE RADICAL SCAVENGER, EDARAVONE, IN THE TREATMENT OF PATIENTS WITH ANEURYSMAL SUBARACHNOID HEMORRHAGE
Akira Munakata (2009)
10.1076/apab.109.2.145.4267
Acute and Delayed Vasoconstriction after Subarachnoid Hemorrhage: Local Cerebral Blood Flow, Histopathology, and Morphology in the Rat Basilar Artery
T. Alkan (2001)
10.1161/01.STR.14.2.270
Mechanisms of relaxant action of nicardipine, a new Ca++‐antagonist, on isolated dog cerebral and mesenteric arteries.
Masahiko Yamamoto (1983)
10.1016/0090-3019(84)90449-X
Analysis of 223 ruptured intracranial aneurysms with special reference to rerupture.
N. Aoyagi (1984)
See more
Semantic Scholar Logo Some data provided by SemanticScholar