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Nanooncology: The Future Of Cancer Diagnosis And Therapy
A. Thakor, S. Gambhir
Published 2013 · Medicine
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In recent years, there has been an unprecedented expansion in the field of nanomedicine with the development of new nanoparticles for the diagnosis and treatment of cancer. Nanoparticles have unique biological properties given their small size and large surface area‐to‐volume ratio, which allows them to bind, absorb, and carry compounds such as small molecule drugs, DNA, RNA, proteins, and probes with high efficiency. Their tunable size, shape, and surface characteristics also enable them to have high stability, high carrier capacity, the ability to incorporate both hydrophilic and hydrophobic substances and compatibility with different administration routes, thereby making them highly attractive in many aspects of oncology. This review article will discuss how nanoparticles are able to function as carriers for chemotherapeutic drugs to increase their therapeutic index; how they can function as therapeutic agents in photodynamic, gene, and thermal therapy; and how nanoparticles can be used as molecular imaging agents to detect and monitor cancer progression. CA Cancer J Clin 2013;63:395‐418. ©2013 American Cancer Society, Inc.
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Inorganic nanoparticles for biomedicine: where materials scientists meet medical research
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Hybrid Imaging: Instrumentation and Data Processing
J. Cal-Gonzalez (2018)
Molecular imaging of breast cancer: present and future directions
D. Alcántara (2014)
F. Chen (2014)
Feedback-mediated cancer therapy: a FRET-based nanoreporter approach
Suproteem K. Sarkar (2014)
Gold nanoparticles prepared by laser ablation in aqueous biocompatible solutions: assessment of safety and biological identity for nanomedicine applications
F. Correard (2014)
Research Trends in Photothermal Therapy Using Gold Nanoparticles
Bong-Geun Kim (2017)
Biocompatibility and biodistribution of suberoylanilide hydroxamic acid loaded poly (DL-lactide-co-glycolide) nanoparticles for targeted drug delivery in cancer.
R. Sankar (2014)
Transport and deposition of nanoparticles in microvascular networks
Hassan M. Al-Siraj (2019)
Non-invasive and quantitative in vivo monitoring of gold nanoparticle concentration and tissue hemodynamics by hybrid optical spectroscopies.
M. Mireles (2019)
Integration of metabolomics and transcriptomics in nanotoxicity studies
T. H. Shin (2018)
Cancer Nanotechnology Plan 2015
M. Davis (2015)
Nanoparticles in Lung Cancer Therapy - Recent Trends
A. Bandyopadhyay (2014)
MOF materials as therapeutic agents, drug carriers, imaging agents and biosensors in cancer biomedicine: Recent advances and perspectives
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