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Use Of Nanoparticles In Tissue Engineering And Regenerative Medicine
Milad Fathi-Achachelouei, Helena Knopf-Marques, Cristiane Evelise Ribeiro da Silva, J. Barthès, E. Bat, A. Tezcaner, N. E. Vrana
Published 2019 · Biology, Medicine
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Advances in nanoparticle (NP) production and demand for control over nanoscale systems have had significant impact on tissue engineering and regenerative medicine (TERM). NPs with low toxicity, contrasting agent properties, tailorable characteristics, targeted/stimuli-response delivery potential, and precise control over behavior (via external stimuli such as magnetic fields) have made it possible their use for improving engineered tissues and overcoming obstacles in TERM. Functional tissue and organ replacements require a high degree of spatial and temporal control over the biological events and also their real-time monitoring. Presentation and local delivery of bioactive (growth factors, chemokines, inhibitors, cytokines, genes etc.) and contrast agents in a controlled manner are important implements to exert control over and monitor the engineered tissues. This need resulted in utilization of NP based systems in tissue engineering scaffolds for delivery of multiple growth factors, for providing contrast for imaging and also for controlling properties of the scaffolds. Depending on the application, materials, as polymers, metals, ceramics and their different composites can be utilized for production of NPs. In this review, we will cover the use of NP systems in TERM and also provide an outlook for future potential use of such systems.
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Nanoparticle-hydrogel superstructures for biomedical applications.
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Nanostructured Materials for Artificial Tissue Replacements
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Biomimetic Cerium Oxide Loaded Gelatin PCL Nanosystems for Wound Dressing on Cutaneous Care Management of Multidrug-Resistant Bacterial Wound Healing
Yi Fei (2020)
Green Plasmonic Nanoparticles and Bio-Inspired Stimuli-Responsive Vesicles in Cancer Therapy Application
Valeria De Matteis (2020)
Critical quality attributes in the development of therapeutic nanomedicines toward clinical translation
M. S. Taha (2020)
Hybrid Bilayer PLA/Chitosan Nanofibrous Scaffolds Doped with ZnO, Fe3O4, and Au Nanoparticles with Bioactive Properties for Skin Tissue Engineering
J. Radwan-Pragłowska (2020)