← Back to Search
Nuclear Signaling Of Plant MAPKs
J. Bigeard, H. Hirt
Published 2018 · Chemistry, Medicine
Download PDFAnalyze on Scholarcy
Mitogen-activated protein kinases (MAPKs) are conserved protein kinases in eukaryotes that establish signaling modules where MAPK kinase kinases (MAPKKKs) activate MAPK kinases (MAPKKs) which in turn activate MAPKs. In plants, they are involved in the signaling of multiple environmental stresses and developmental programs. MAPKs phosphorylate their substrates and this post-translational modification (PTM) contributes to the regulation of proteins. PTMs may indeed modify the activity, subcellular localization, stability or trans-interactions of modified proteins. Plant MAPKs usually localize to the cytosol and/or nucleus, and in some instances they may also translocate from the cytosol to the nucleus. Upon the detection of environmental changes at the cell surface, MAPKs participate in the signal transduction to the nucleus, allowing an adequate transcriptional reprogramming. The identification of plant MAPK substrates largely contributed to a better understanding of the underlying signaling mechanisms. In this review, we highlight the nuclear signaling of plant MAPKs. We discuss the activation, regulation and activity of plant MAPKs, as well as their nuclear re-localization. We also describe and discuss known nuclear substrates of plant MAPKs in the context of biotic stress, abiotic stress and development and consider future research directions in the field of plant MAPKs.
This paper references
Mechanisms of specificity in protein phosphorylation
J. Ubersax (2007)
Phosphorylation of the transcriptional regulator MYB44 by mitogen activated protein kinase regulates Arabidopsis seed germination.
X. C. Nguyen (2012)
The molecular architecture of the plant nuclear pore complex.
K. Tamura (2013)
Dual-Level Regulation of ACC Synthase Activity by MPK3/MPK6 Cascade and Its Downstream WRKY Transcription Factor during Ethylene Induction in Arabidopsis
Guojing Li (2012)
Diversity, classification and function of the plant protein kinase superfamily
Melissa D. Lehti-Shiu (2012)
Soybean MAPK, GMK1 Is dually regulated by phosphatidic acid and hydrogen peroxide and translocated to nucleus during salt stress
J. H. Im (2012)
MicroRNA biogenesis factor DRB1 is a phosphorylation target of mitogen activated protein kinase MPK3 in both rice and Arabidopsis
B. Raghuram (2015)
A conserved docking motif in MAP kinases common to substrates, activators and regulators
T. Tanoue (2000)
MAPK Phosphatase AP2C3 Induces Ectopic Proliferation of Epidermal Cells Leading to Stomata Development in Arabidopsis
Julija Umbrasaite (2010)
Phosphorylation of Trihelix Transcriptional Repressor ASR3 by MAP KINASE4 Negatively Regulates Arabidopsis Immunity
Bo Li (2015)
Comprehensive gene expression atlas for the Arabidopsis MAP kinase signalling pathways.
M. Menges (2008)
Direct Phosphorylation and Activation of a Mitogen-Activated Protein Kinase by a Calcium-Dependent Protein Kinase in Rice[C][W]
Kabin Xie (2014)
Distinct osmo-sensing protein kinase pathways are involved in signalling moderate and severe hyper-osmotic stress
The Sequence of the Human Genome
J. Venter (2001)
The BASL polarity protein controls a MAPK signaling feedback loop in asymmetric cell division.
Ying Zhang (2015)
Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase
N. Anderson (1990)
The MPK6-ERF6-ROS-Responsive cis-Acting Element7/GCC Box Complex Modulates Oxidative Gene Transcription and the Oxidative Response in Arabidopsis1[W][OA]
P. Wang (2013)
A cotton group C MAP kinase gene, GhMPK2, positively regulates salt and drought tolerance in tobacco
L. Zhang (2011)
Deciphering post‐translational modification codes
Adam P Lothrop (2013)
Nuclear protein kinases: still enigmatic components in plant cell signalling.
J. Dahan (2010)
Abscisic acid and hydrogen peroxide induce a novel maize group C MAP kinase gene, ZmMPK7, which is responsible for the removal of reactive oxygen species
Xiao-juan Zong (2008)
VIP1 response elements mediate mitogen-activated protein kinase 3-induced stress gene expression
A. Pitzschke (2009)
Phosphorylation of the Nicotiana benthamiana WRKY8 Transcription Factor by MAPK Functions in the Defense Response[C][W][OA]
N. Ishihama (2011)
OsBWMK1 mediates SA-dependent defense responses by activating the transcription factor OsWRKY33.
S. C. Koo (2009)
MPK3- and MPK6-Mediated ICE1 Phosphorylation Negatively Regulates ICE1 Stability and Freezing Tolerance in Arabidopsis.
H. Li (2017)
Pathogen-Responsive MPK3 and MPK6 Reprogram the Biosynthesis of Indole Glucosinolates and Their Derivatives in Arabidopsis Immunity[OPEN]
Juan Xu (2016)
The MAP kinase substrate MKS1 is a regulator of plant defense responses
E. Andréasson (2005)
Regulation of WRKY46 Transcription Factor Function by Mitogen-Activated Protein Kinases in Arabidopsis thaliana
A. Sheikh (2016)
Calcium/calmodulin-regulated receptor-like kinase CRLK1 interacts with MEKK1 in plants.
T. Yang (2010)
Scaffolds: interaction platforms for cellular signalling circuits.
András Zeke (2009)
Identification and analysis ofMKK andMPK gene families in canola (Brassica napus L.)
W. Liang (2013)
The MAP Kinase MPK4 Is Required for Cytokinesis in Arabidopsis thaliana[W]
Ken Kosetsu (2010)
Phosphorylation and Stabilization of Arabidopsis MAP Kinase Phosphatase 1 in Response to UV-B Stress*
Marina A González Besteiro (2012)
Involvement of the mitogen‐activated protein kinase SIMK in regulation of root hair tip growth
Jozef Šamaj (2002)
Emerging functions for plant MAP kinase phosphatases.
Sebastian Bartels (2010)
Identification and analysis of MKK and MPK gene families in canola (Brassica napus L.)
W. Liang (2013)
Composition of the plant nuclear envelope: theme and variations.
I. Meier (2007)
Phosphorylation of NtMAP65-1 by a MAP kinase down-regulates its activity of microtubule bundling and stimulates progression of cytokinesis of tobacco cells.
M. Sasabe (2006)
MAPKK-Independent Activation of p38α Mediated by TAB1-Dependent Autophosphorylation of p38α
Baoxue Ge (2002)
Control of the AtMAP65-1 interaction with microtubules through the cell cycle
A. Smertenko (2006)
Activation Mechanism of the MAP Kinase ERK2 by Dual Phosphorylation
B. Canagarajah (1997)
Mitogen-activated protein kinase 4 is involved in the regulation of mitotic and cytokinetic microtubule transitions in Arabidopsis thaliana.
M. Beck (2011)
The Ste5 Scaffold Directs Mating Signaling by Catalytically Unlocking the Fus3 MAP Kinase for Activation
Matthew C Good (2009)
Determination of primary sequence specificity of Arabidopsis MAPKs MPK3 and MPK6 leads to identification of new substrates.
C. Sörensson (2012)
Substrate Discrimination among Mitogen-activated Protein Kinases through Distinct Docking Sequence Motifs*
D. Sheridan (2008)
Emerging topics in the cell biology of mitogen-activated protein kinases.
O. Šamajová (2013)
OsWRKY30 is activated byMAP kinases to confer drought tolerance in rice
H. Shen (2012)
Receptor-mediated activation of a MAP kinase in pathogen defense of plants.
W. Ligterink (1997)
Exploring the evolutionary path of plant MAPK networks.
R. Dóczi (2012)
Dual control of nuclear EIN3 by bifurcate MAPK cascades in C2H4 signalling
Sangdong Yoo (2008)
Abscisic acid and hydrogen peroxide induce a novel maize group CMAP kinase gene , ZmMPK 7 , which is responsible for the removal of reactive oxygen species
X. Zong (2009)
Initial sequencing and analysis of the human genome
International Human Genome Sequencing Consortium (2001)
A mitogen-activated protein kinase, AhMPK6 from peanut localizes to the nucleus and also induces defense responses upon transient expression in tobacco.
K. R. Kumar (2010)
Mitogen-activated protein kinase signaling in plants.
M. C. Rodriguez (2010)
Essential role of ERK dimers in the activation of cytoplasmic but not nuclear substrates by ERK-scaffold complexes.
B. Casar (2008)
Opposite functions of a rice mitogen-activated protein kinase during the process of resistance against Xanthomonas oryzae.
Xiangling Shen (2010)
Identification of Novel in vivo MAP Kinase Substrates in Arabidopsis thaliana Through Use of Tandem Metal Oxide Affinity Chromatography*
W. Hoehenwarter (2012)
The Pseudomonas syringae type III effector tyrosine phosphatase HopAO1 suppresses innate immunity in Arabidopsis thaliana.
William R Underwood (2007)
Identification of the regulatory phosphorylation sites in pp42/mitogen‐activated protein kinase (MAP kinase).
D. M. Payne (1991)
Identification and characterization of an ABA-activated MAP kinase cascade in Arabidopsis thaliana.
Agyemang Danquah (2015)
Activation of the Arabidopsis thaliana mitogen-activated protein kinase MPK11 by the flagellin-derived elicitor peptide, flg22.
Gerit Bethke (2012)
Phosphorylation‐dependent regulation of plant chromatin and chromatin‐associated proteins
J. Bigeard (2014)
FLS2: an LRR receptor-like kinase involved in the perception of the bacterial elicitor flagellin in Arabidopsis.
L. Gómez-Gómez (2000)
The Arabidopsis Mitogen-Activated Protein Kinase Kinase Kinase 20 (MKKK20) Acts Upstream of MKK3 and MPK18 in Two Separate Signaling Pathways Involved in Root Microtubule Functions
Rachid Benhamman (2017)
Status of Large-scale Analysis of Post-translational Modifications by Mass Spectrometry*
J. Olsen (2013)
A conserved motif at the amino termini of MEKs might mediate high-affinity interaction with the cognate MAPKs.
L. Bardwell (1996)
Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3.
P. McDonald (2000)
Themolecular architecture of the plant nuclear pore complex
K. Tamura (2013)
The sequence of the human
J. C. Venter (2001)
Phosphorylation of Tyr-176 of the Yeast MAPK Hog1/p38 Is Not Vital for Hog1 Biological Activity* 210
M. Bell (2003)
Convergence and specificity in the Arabidopsis MAPK nexus.
E. Andreasson (2010)
Phosphorylation of a WRKY Transcription Factor by Two Pathogen-Responsive MAPKs Drives Phytoalexin Biosynthesis in Arabidopsis[C][W]
Guohong Mao (2011)
GhMPK16, a novel stress-responsive group D MAPK gene from cotton, is involved in disease resistance and drought sensitivity
J. Shi (2011)
A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation
M. J. Robinson (1998)
Phosphorylation of the Polarity Protein BASL Differentiates Asymmetric Cell Fate through MAPKs and SPCH
Ying Zhang (2016)
Cotton GhMPK6a negatively regulates osmotic tolerance and bacterial infection in transgenic Nicotiana benthamiana, and plays a pivotal role in development
Y. Li (2013)
MtMAPKK4 is an essential gene for growth and reproduction of Medicago truncatula.
Tao Chen (2017)
PhosPhAt: the Arabidopsis thaliana phosphorylation site database. An update
Pawel Durek (2010)
MAP Kinase Cascades Regulate the Cold Response by Modulating ICE1 Protein Stability.
C. Zhao (2017)
Sequence the Human Genome
D. Mccormick (1986)
Arabidopsis MPK3 and MPK6 Play Different Roles in Basal and Oligogalacturonide- or Flagellin-Induced Resistance against Botrytis cinerea1[W]
R. Galletti (2011)
MEKK1 Is Required for flg22-Induced MPK4 Activation in Arabidopsis Plants1[C][W]
M. Suarez-Rodriguez (2006)
Nucleocytoplasmic transport: taking an inventory
H. Fried (2003)
Arabidopsis LIP5, a Positive Regulator of Multivesicular Body Biogenesis, Is a Critical Target of Pathogen-Responsive MAPK Cascade in Plant Basal Defense
F. Wang (2014)
MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha.
Baoxue Ge (2002)
Nucleocytoplasmic partitioning of tobacco N receptor is modulated by SGT1.
Rafał Hoser (2013)
High Throughput Identification of Potential Arabidopsis Mitogen-activated Protein Kinases Substrates*S
Tanja Feilner (2005)
Phosphorylation of NtMAP65-1 by a MAP kinase down-regulates its Frontiers in Plant Science
M. Sasabe (2006)
Quantitative Phosphoproteomic Analysis Reveals Shared and Specific Targets of Arabidopsis Mitogen-Activated Protein Kinases (MAPKs) MPK3, MPK4, and MPK6*
N. Rayapuram (2017)
Systematic Trans-Genomic Comparison of Protein Kinases between Arabidopsis and Saccharomyces cerevisiae1
D. Wang (2003)
Arabidopsis MEKK1 can take a short cut: it can directly interact with senescence-related WRKY53 transcription factor on the protein level and can bind to its promoter
Ying Miao (2007)
A MAPK pathway mediates ethylene signaling in plants
F. Ouaked (2003)
Arabidopsis MAPKs: a complex signalling network involved in multiple biological processes.
J. Colcombet (2008)
Arabidopsis MAPK Phosphatase 2 (MKP2) Positively Regulates Oxidative Stress Tolerance and Inactivates the MPK3 and MPK6 MAPKs*
J. S. Lee (2007)
The Arabidopsis Mitogen-Activated Protein Kinase Phosphatase PP2C5 Affects Seed Germination, Stomatal Aperture, and Abscisic Acid-Inducible Gene Expression1[C][W]
A. K. Brock (2010)
Overexpression of Cotton GhMPK11 Decreases Disease Resistance through the Gibberellin Signaling Pathway in Transgenic Nicotiana benthamiana
F. Wang (2016)
Multisite phosphorylation provides sophisticated regulation of transcription factors.
C. Holmberg (2002)
A novel mitogen-activated protein kinase gene in maize (Zea mays), ZmMPK3, is involved in response to diverse environmental cues.
J. Wang (2010)
Working Without Kinase Activity: Phosphotransfer-Independent Functions of Extracellular Signal–Regulated Kinases
J. Rodríguez (2011)
Arabidopsis Stomatal Initiation Is Controlled by MAPK-Mediated Regulation of the bHLH SPEECHLESS
G. Lampard (2008)
Arabidopsis MKK10-MPK6 mediates red-light-regulated opening of seedling cotyledons through phosphorylation of PIF3
Xiaoyun Xin (2018)
OsWRKY30 is activated by MAP kinases to confer drought tolerance in rice
H. Shen (2012)
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
The Arabidopsis Genome Initiative (2000)
Silencing MPK4 in Nicotiana attenuata Enhances Photosynthesis and Seed Production But Compromises Abscisic Acid-Induced Stomatal Closure and Guard Cell-Mediated Resistance to Pseudomonas syringae pv tomato DC30001[W]
C. Hettenhausen (2011)
Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions.
R. Biondi (2003)
Isolation of ATMEKK1 (a MAP kinase kinase kinase)-interacting proteins and analysis of a MAP kinase cascade in Arabidopsis.
K. Ichimura (1998)
Dual Regulation of Gene Expression Mediated by Extended MAPK Activation and Salicylic Acid Contributes to Robust Innate Immunity in Arabidopsis thaliana
Kenichi Tsuda (2013)
Constitutively Active Mitogen-Activated Protein Kinase Versions Reveal Functions of Arabidopsis MPK4 in Pathogen Defense Signaling[C][W]
Souha Berriri (2012)
Proteome-wide post-translational modification statistics: frequency analysis and curation of the swiss-prot database
G. Khoury (2011)
Activation of defense response pathways by OGs and Flg22 elicitors in Arabidopsis seedlings.
Carine Denoux (2008)
MAPK phosphatase MKP2 mediates disease responses in Arabidopsis and functionally interacts with MPK3 and MPK6.
V. Lumbreras (2010)
Interplay between calcium signalling and early signalling elements during defence responses to microbe- or damage-associated molecular patterns.
Stefanie Ranf (2011)
The mRNA decay factor PAT1 functions in a pathway including MAP kinase 4 and immune receptor SUMM2
Milena Roux (2015)
Arabidopsis Protein Phosphatase DBP1 Nucleates a Protein Network with a Role in Regulating Plant Defense
J. L. Carrasco (2014)
Arabidopsis MAP3K16 and Other Salt-Inducible MAP3Ks Regulate ABA Response Redundantly
Seo-wha Choi (2017)
Perception of the Bacterial PAMP EF-Tu by the Receptor EFR Restricts Agrobacterium-Mediated Transformation
C. Zipfel (2006)
Salt Stress in Arabidopsis: Lipid Transfer Protein AZI1 and Its Control by Mitogen-Activated Protein Kinase MPK3
A. Pitzschke (2014)
Alternative splicing of the OsBWMK1 gene generates three transcript variants showing differential subcellular localizations.
S. C. Koo (2007)
Soybean Homologs of MPK4 Negatively Regulate Defense Responses and Positively Regulate Growth and Development1[W][OA]
Jian-Zhong Liu (2011)
The N-Terminal Domain of ERK1 Accounts for the Functional Differences with ERK2
M. Marchi (2008)
EDR1 Physically Interacts with MKK4/MKK5 and Negatively Regulates a MAP Kinase Cascade to Modulate Plant Innate Immunity
C. Zhao (2014)
TMKP1 is a novel wheat stress responsive MAP kinase phosphatase localized in the nucleus
Ikram Zaïdi (2010)
Dynamic Changes in the Localization of MAPK Cascade Components Controlling Pathogenesis-related (PR) Gene Expression during Innate Immunity in Parsley*
J. Lee (2004)
Arabidopsis MPK6 is involved in cell division plane control during early root development, and localizes to the pre-prophase band, phragmoplast, trans-Golgi network and plasma membrane.
J. Mueller (2010)
Ancient signals: comparative genomics of plant MAPK and MAPKK gene families.
L. Hamel (2006)
Tight Interconnection and Multi-Level Control of Arabidopsis MYB44 in MAPK Cascade Signalling
H. Persak (2013)
Phosphorylation of an ERF Transcription Factor by Arabidopsis MPK3/MPK6 Regulates Plant Defense Gene Induction and Fungal Resistance[C][W]
Xiangzong Meng (2013)
Trojan Horse Strategy in Agrobacterium Transformation : Abusing MAPK Defense Signaling
N. Brissett (2007)
MAP kinases MPK9 and MPK12 are preferentially expressed in guard cells and positively regulate ROS-mediated ABA signaling
Fabien Jammes (2009)
Functional Involvement of a Mitogen Activated Protein Kinase Module, OsMKK3-OsMPK7-OsWRK30 in Mediating Resistance against Xanthomonas oryzae in Rice
S. K. Jalmi (2016)
Phosphorylation of the zinc finger transcriptional regulator ZAT6 by MPK6 regulates Arabidopsis seed germination under salt and osmotic stress.
Xuanming Liu (2013)
Cell-signalling dynamics in time and space
B. Kholodenko (2006)
Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase.
D. Jacobs (1999)
Transactivation of wound-responsive genes containing the core sequence of the auxin-responsive element by a wound-induced protein kinase-activated transcription factor in tobacco plants
Kwi-Mi Chung (2007)
Quantitative phosphoproteomic analysis reveals shared and specific targets of Arabidopsis MPK3, MPK4 and MPK6
N. Rayapuram (2017)
A mitogen-activated protein kinase gene, AhMPK3 of peanut: molecular cloning, genomic organization, and heterologous expression conferring resistance against Spodoptera litura in tobacco
K. R. Kumar (2009)
Ultrastructural distribution of a MAP kinase and transcripts in quiescent and cycling plant cells and pollen grains.
G. Préstamo (1999)
The Rice Kinase Database. A Phylogenomic Database for the Rice Kinome1[OA]
C. Dardick (2006)
Tuning Bulk Electrostatics to Regulate Protein Function
Z. Serber (2007)
A Mitogen-Activated Protein Kinase Cascade Module, MKK3-MPK6 and MYC2, Is Involved in Blue Light-Mediated Seedling Development in Arabidopsis[C][W]
Vishmita Sethi (2014)
The regulation of protein function by multisite phosphorylation--a 25 year update.
P. Cohen (2000)
The Arabidopsis thaliana mitogen-activated protein kinases MPK3 and MPK6 target a subclass of 'VQ-motif'-containing proteins to regulate immune responses.
Pascal Pecher (2014)
A Critical Role of Lyst-Interacting Protein5, a Positive Regulator of Multivesicular Body Biogenesis, in Plant Responses to Heat and Salt Stresses1
F. Wang (2015)
Mitogen-activated protein kinase cascades in plants: a new nomenclature.
Kazuya Ichimura (2002)
MAP kinase cascades regulate the cold response bymodulating ICE1 protein stability. Dev. Cell 43, 618.e5–629.e5
C. Zhao (2017)
A Positive Feedback Loop Governed by SUB1A1 Interaction with MITOGEN-ACTIVATED PROTEIN KINASE3 Imparts Submergence Tolerance in Rice
P. Singh (2016)
The cotton MAPK kinase GhMPK20 negatively regulates resistance to Fusarium oxysporum by mediating the MKK4-MPK20-WRKY40 cascade.
Chen Wang (2018)
Stimulus-Coupled Spatial Restriction of Extracellular Signal-Regulated Kinase 1/2 Activity Contributes to the Specificity of Signal-Response Pathways
Angelique W Whitehurst (2004)
The MKK2 pathway mediates cold and salt stress signaling in Arabidopsis.
M. Teige (2004)
ZmMPK17, a novel maize group D MAP kinase gene, is involved in multiple stress responses
Jiaowen Pan (2011)
Regulation of the heat stress response in Arabidopsis by MPK6-targeted phosphorylation of the heat stress factor HsfA2
A. Evrard (2013)
Activation of a Novel Transcription Factor through Phosphorylation by WIPK, a Wound-Induced Mitogen-Activated Protein Kinase in Tobacco Plants1
Yun-Kiam Yap (2005)
MAP kinase-mediated negative regulation of symbiotic nodule formation inMedicago truncatula.Mol. Cells
H. Ryu (2017)
Amitogen-activated protein kinase gene, AhMPK3 of peanut: molecular cloning, genomic organization, and heterologous expression conferring resistance against Spodoptera litura in tobacco.Mol
K.R.R. Kumar (2009)
Tobacco transcription factor WRKY1 is phosphorylated by the MAP kinase SIPK and mediates HR-like cell death in tobacco.
F. Menke (2005)
Calmodulin-dependent activation of MAP kinase for ROS homeostasis in Arabidopsis.
F. Takahashi (2011)
Alternative p38 activation pathway mediated by T cell receptor–proximal tyrosine kinases
J. Salvador (2005)
MEKK1, MKK1/MKK2 and MPK4 function together in a mitogen-activated protein kinase cascade to regulate innate immunity in plants
M. Gao (2008)
Tomato 14-3-3 Protein TFT7 Interacts with a MAP Kinase Kinase to Regulate Immunity-associated Programmed Cell Death Mediated by Diverse Disease Resistance Proteins*
C. Oh (2011)
Identification of Phosphoinositide-Binding Protein PATELLIN2 as a Substrate of Arabidopsis MPK4 MAP Kinase during Septum Formation in Cytokinesis
T. Suzuki (2016)
Salt-induced subcellular kinase relocation and seedling susceptibility caused by overexpression of Medicago SIMKK in Arabidopsis
M. Ovečka (2014)
BWMK1, a Rice Mitogen-Activated Protein Kinase, Locates in the Nucleus and Mediates Pathogenesis-Related Gene Expression by Activation of a Transcription Factor1
Y. Cheong (2003)
Diverse stress signals activate the C1 subgroup MAP kinases of Arabidopsis
D. Ortiz-Masia (2007)
A Basic Helix-Loop-Helix Transcription Factor in Arabidopsis, MYC2, Acts as a Repressor of Blue Light–Mediated Photomorphogenic Growthw⃞
V. Yadav (2005)
OsMPK3 is a TEY-type rice MAPK in Group C and phosphorylates OsbHLH65, a transcription factor binding to the E-box element
Hyun-Young Shin (2014)
Functional analysis of Arabidopsis immune-related MAPKs uncovers a role for MPK3 as negative regulator of inducible defences
Nicolas Frei dit Frey (2013)
EFR restricts Agrobacterium-mediated transformation
X. Zong (2009)
The Arabidopsis tandem zinc finger 9 protein binds RNA and mediates pathogen-associated molecular pattern-triggered immune responses.
L. D. Maldonado-Bonilla (2014)
Stress hormone-independent activation and nuclear translocation of mitogen-activated protein kinases in Arabidopsis thaliana during ozone exposure.
Reetta Ahlfors (2004)
MAP Kinase-Mediated Negative Regulation of Symbiotic Nodule Formation in Medicago truncatula
Hojin Ryu (2017)
MAPKs entry into the nucleus at specific interchromatin domains in plant differentiation and proliferation processes.
M. Coronado (2002)
Mechanisms of MAPK signalling specificity.
L. Bardwell (2006)
The PP2C-Type Phosphatase AP2C1, Which Negatively Regulates MPK4 and MPK6, Modulates Innate Immunity, Jasmonic Acid, and Ethylene Levels in Arabidopsis[W]
A. Schweighofer (2007)
The rice kinase database
C. Dardick (2007)
Microbial Elicitors Induce Activation and Dual Phosphorylation of the Arabidopsis thaliana MAPK 6*
T. Nühse (2000)
GhMPK7, a novel multiple stress-responsive cotton group C MAPK gene, has a role in broad spectrum disease resistance and plant development
J. Shi (2010)
Pathogen-Secreted Proteases Activate a Novel Plant Immune Pathway
Zhenyu Cheng (2015)
MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays.
Sorina C. Popescu (2009)
Scaffold Proteins: Hubs for Controlling the Flow of Cellular Information
Matthew C Good (2011)
Deciphering a global network of functionally associated post-translational modifications
Pablo Minguez (2012)
Arabidopsis MAP kinase phosphatase 1 is phosphorylated and activated by its substrate AtMPK6
H. Park (2011)
The age of crosstalk: phosphorylation, ubiquitination, and beyond.
T. Hunter (2007)
The heat shock factor A4A confers salt tolerance and is regulated by oxidative stress and the mitogen-activated protein kinases MPK3 and MPK6
I. Pérez-Salamó (2014)
Interaction between two rice mitogen activated protein kinases and its possible role in plant defense
A. Sheikh (2012)
Flg22 regulates the release of an ethylene response factor substrate from MAP kinase 6 in Arabidopsis thaliana via ethylene signaling
Gerit Bethke (2009)
This paper is referenced by
ABA inhibits myristoylation and induces shuttling of the RGLG1 E3 ligase to promote nuclear degradation of PP2CA.
Borja Belda-Palazón (2019)
Analysis of the Barley Cereal Cyst Nematode Resistance Locus Rha2
Van Gansbeke (2019)
The mitogen-activated protein kinase 4-phosphorylated heat shock factor A4A regulates responses to combined salt and heat stresses
Nórbert Andrási (2019)
StMAPK3 controls oxidase activity, photosynthesis and stomatal aperture under salinity and osmosis stress in potato.
Xi Zhu (2020)
(Z)-3-Hexenol Induces Tea Defense against Ectropis grisescens in the Field
S. Chen (2020)
Rice Calcium/Calmodulin-Dependent Protein Kinase Directly Phosphorylates a Mitogen-Activated Protein Kinase Kinase to Regulate Abscisic Acid Responses
Min Chen (2020)
Transcriptomic analysis of pepper plants provides insights into host responses to Fusarium solani infestation.
Tiing Lau Ee (2020)
Early Root Transcriptomic Changes in Wheat Seedlings Colonized by Trichoderma harzianum Under Different Inorganic Nitrogen Supplies
M. B. Rubio (2019)
Arabidopsis MAPK signaling pathways and their cross talks in abiotic stress response
K. Kumar (2020)
Polyamine Homeostasis in Tomato Biotic/Abiotic Stress Cross-Tolerance.
Georgios Tsaniklidis (2019)
Negative impact of recipient SPRED2 deficiency on transplanted lung in a mouse model.
K. Hashimoto (2019)
Genome-wide characterization and expression profiling of MAPK cascade genes in Salvia miltiorrhiza reveals the function of SmMAPK3 and SmMAPK1 in secondary metabolism
Yongfeng Xie (2020)
Transcriptome Profiling of Haloxylon persicum (Bunge ex Boiss and Buhse) an Endangered Plant Species under PEG-Induced Drought Stress
Fayas Thayale Purayil (2020)
MAPK Enzymes: a ROS Activated Signaling Sensors Involved in Modulating Heat Stress Response, Tolerance and Grain Stability of Wheat under Heat Stress
R. Kumar (2020)
A Disease Resistance Elicitor Laminarin Enhances Tea Defense against a Piercing Herbivore Empoasca (Matsumurasca) onukii Matsuda
Zhaojun Xin (2019)
Identification of the MAPK Cascade and its Relationship with Nitrogen Metabolism in the Green Alga Chlamydomonas reinhardtii
Aitor Gomez-Osuna (2020)
Stepwise signal transduction cascades under salt stress in leaves of wild barley (Hordeum spontaneum)
Aala A Abulfaraj (2020)
Pharmaceuticals in treated wastewater induce a stress response in tomato plants
R. Gorovits (2020)
Plants and heavy metals: perception and signaling
N. A. Belyavskaya (2018)
The role of SIPK signaling pathway in antioxidant activity and programmed cell death of tobacco cells after exposure to cadmium.
M. Pormehr (2019)
Can wheat survive in heat? Assembling tools towards successful development of heat stress tolerance in Triticum aestivum L.
Ranjeet Kaur (2019)
The subcellular organisation of Saccharomyces cerevisiae
D. J. Nightingale (2019)
Accelerated ageing induces physiological and biochemical changes in tomato seeds involving MAPK pathways
Manisha Nigam (2019)
Plant Molecular Responses to Potato Virus Y: A Continuum of Outcomes from Sensitivity and Tolerance to Resistance
Š. Baebler (2020)
Emerging mechanisms to fine-tune receptor kinase signaling specificity.
Sergio Galindo-Trigo (2020)
Mitogen-Activated Protein Kinase Cascades in Plant Hormone Signaling
Przemysław Jagodzik (2018)
Cellular Complexity in MAPK Signaling in Plants: Questions and Emerging Tools to Answer Them
P. Krysan (2018)
Wounding and insect feeding trigger two independent MAPK pathways with distinct regulation and kinetics
Cécile Sözen (2019)
Post-translational modifications drive plant cell differentiation
Víctor Aguilar-Hernández (2020)
The Winner Takes It All: Auxin—The Main Player during Plant Embryogenesis
K. Winnicki (2020)
(E)-Nerolidol is a volatile signal that induces defenses against insects and pathogens in tea plants
Shenglong Chen (2020)
Wounding and Insect Feeding Trigger Two Independent MAPK Pathways with Distinct Regulation and Kinetics[OPEN]
Cécile Sözen (2020)See more