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Carbon Dots As Promising Tools For Cancer Diagnosis And Therapy

Giuseppe Nocito, Giovanna Calabrese, Stefano Forte, Salvatore Petralia, Caterina Puglisi, Michela Campolo, Emanuela Esposito, Sabrina Conoci

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Carbon Dots (CDs) are the latest members of carbon-based nanomaterials, which since their discovery have attracted notable attention due to their chemical and mechanical properties, brilliant fluorescence, high photostability, and good biocompatibility. Together with the ease and affordable preparation costs, these intrinsic features make CDs the most promising nanomaterials for multiple applications in the biological field, such as bioimaging, biotherapy, and gene/drug delivery. This review will illustrate the most recent applications of CDs in the biomedical field, focusing on their biocompatibility, fluorescence, low cytotoxicity, cellular uptake, and theranostic properties to highlight above all their usefulness as a promising tool for cancer diagnosis and therapy.