Online citations, reference lists, and bibliographies.
← Back to Search

Pressurized Intraperitoneal Aerosol Chemotheprapy After Misdiagnosed Gastric Cancer: Case Report And Review Of The Literature

M. Nowacki, D. Grzanka, W. Zegarski
Published 2018 · Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
We report the first application of pressurized intraperitoneal aerosol chemotherapy (PIPAC) as a rescue therapy before palliative D2 gastrectomy combined with liver metastasectomy performed in a 49-year-old woman with peritoneal carcinomatosis who was primarily diagnosed with and underwent surgery for a Krukenberg tumor. The PIPAC procedure was performed with the use of cisplatin at 7.5 mg/m2 and doxorubicin at 1.5 mg/m2 for 30 min at 37 °C. Eight weeks after the PIPAC procedure, the patient underwent open classic D2 gastrectomy with the creation of a Roux-en-Y anastomosis (RNY) combined with liver metastasectomy. The patient underwent the classic protocol for chemotherapy combined with Xeloda. The patient felt better and returned to her daily activities. Multicenter data should be gathered to confirm the usefulness of PIPAC as a rescue or neoadjuvant supportive therapy in a very select group of patients who have been recently qualified to undergo classic chemotherapy or standard oncologic surgical procedures.
This paper references
10.18632/ONCOTARGET.4309
Nanovehicles as a novel target strategy for hyperthermic intraperitoneal chemotherapy: a multidisciplinary study of peritoneal carcinomatosis
Maciej Nowacki (2015)
10.1371/journal.pone.0186709
Pressurized Intra Peritoneal Aerosol Chemotherapy in patients suffering from peritoneal carcinomatosis of pancreatic adenocarcinoma
T. Khosrawipour (2017)
10.1186/s12904-017-0192-1
Palliative gastrectomy is beneficial in selected cases of metastatic gastric cancer
Jun-Te Hsu (2017)
10.1097/01.sla.0000149300.28588.23
Gastric Adenocarcinoma: Review and Considerations for Future Directions
B. Dicken (2005)
10.1097/00042737-200111000-00023
Helicobacter pylori infection and the development of gastric cancer.
R. P. Blankfield (2002)
10.1155/2014/797429
A Krukenberg Tumor from an Occult Intramucosal Gastric Carcinoma Identified during an Autopsy
Y. Nakamura (2014)
10.1186/s12957-016-1087-y
Clinical analysis of Krukenberg tumours in patients with colorectal cancer—a review of 57 cases
K. Xu (2017)
Metastasectomy of Krukenberg tumors may be associated with survival benefits in patients with metastatic gastric cancer.
L. Lu (2012)
[Gastric cancer].
H. Espejo (1996)
10.1056/NEJMOA001999
Helicobacter pylori infection and the development of gastric cancer.
N. Uemura (2001)
10.1016/J.GMIT.2013.02.006
Identification of prognostic factors for Krukenberg tumor
W. Lu (2013)
10.1016/S1068-607X(98)00047-X
Management of Krukenberg tumors: an 11-year experience and review of the literature.
McGill (1998)
10.1007/s10120-002-0203-6
The epidemiology of gastric cancer
D. Roder (2002)
10.3802/jgo.2017.28.e80
Nutritional status, cachexia, and anorexia in women with peritoneal metastasis and intraperitoneal chemotherapy: a longitudinal analysis
Ziad Hilal (2017)
10.5348/IJCRI-2016128-CR-10716
Diffuse gastric cancer with Krukenberg tumor: A case report
Manraj Khosla (2016)
10.1136/bcr.12.2010.3597
Krukenberg tumour arising from adenocarcinoma of the gastro-oesophageal junction in a 28-year-old female presenting as lower abdominal swelling mimicking an inguinal hernia
H. Matar (2011)
10.1007/s13277-012-0571-4
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy improves the survival of gastric cancer patients with ovarian metastasis and peritoneal dissemination
Xiao-jiang Wu (2012)
11 and outcome of gastric cancer
HE Matar (2008)
gastric origin versus colorectal origin
KY Xu (2015)
Delay in diagnosis and treatment of gastric cancer: from the beginning of symptoms to surgery--an Iranian study.
Seyed Nejat Hosseini (2007)
10.4236/ARSCI.2016.42005
An Up-to-Date Understanding of the “Krukenberg Tumor” Mechanism
B. Shah (2016)
10.1016/j.ejso.2017.03.019
Pressurized IntraPeritoneal Aerosol Chemotherapy - Practical aspects.
M. Huebner (2017)
10.5772/56736
Surgical Treatment
Enrico Sebastiani (2018)
10.1002/ijc.24290
Recent patterns in gastric cancer: A global overview
P. Bertuccio (2009)
10.1016/j.ejso.2017.09.010
Multicentric initial experience with the use of the pressurized intraperitoneal aerosol chemotherapy (PIPAC) in the management of unresectable peritoneal carcinomatosis.
M. Alyami (2017)
10.1002/ijc.29210
Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
J. Ferlay (2015)
10.1016/j.canep.2016.03.008
Stomach cancer burden in Central and South America.
M. Sierra (2016)
10.5468/ogs.2015.58.1.32
Krukenberg tumors of gastric origin versus colorectal origin
Yi Jo Jeung (2015)
10.4143/crt.2013.175
Comparison of Surgery Plus Chemotherapy and Palliative Chemotherapy Alone for Advanced Gastric Cancer with Krukenberg Tumor
J. Cho (2015)
10.1007/s10585-017-9849-7
Peritoneal metastasis from pancreatic cancer treated with pressurized intraperitoneal aerosol chemotherapy (PIPAC)
M. Graversen (2017)
10.3748/WJG.14.1149
Role of symptoms in diagnosis and outcome of gastric cancer.
G. Maconi (2008)
10.4103/1011-4564.192838
Treatment of Krukenberg tumor with hyperthermic intraperitoneal chemotherapy: A report of three cases
L. Chen (2016)
10.1016/j.ejso.2008.05.006
Surgical treatment for patients with different origins of Krukenberg tumors: outcomes and prognostic factors.
R. Jiang (2009)
10.1186/s12957-016-1008-0
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) as a neoadjuvant therapy before cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
Ramy Girshally (2016)
10.3748/wjg.v20.i16.4483
Characteristics of gastric cancer in Asia.
R. Rahman (2014)
10.1007/s10585-017-9856-8
The pathogenesis, diagnosis, and management of metastatic tumors to the ovary: a comprehensive review
O. Kubeček (2017)
10.1634/theoncologist.2016-0230
Cancer Control in Central and Eastern Europe
C. la Vecchia (2016)



This paper is referenced by
Semantic Scholar Logo Some data provided by SemanticScholar