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Multifunctional Nanocomposites For Biotherapeutic Applications

Eliana B. Souto, A. R. Fernandes, J. Dias Ferreira, C. F. da Silva, Patrícia Severino, Carlos Martins-Gomes, Amélia M. Silva

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The rationale for administering a drug is usually related to the increase of the drug bioavailability with the aim to achieve a therapeutic effect at a predetermined time. A drug delivery system consists of a formulation or even a device that introduces a drug into the organism being capable of assuring the efficacy and safety by controlling the rate, time, and place of release. With the field of multifunctional nanocomposites, crucial factors such as the improvement on the medicine's efficacy, reduced economic implications, extended life of product patent, better safety and efficacy profile, and increased compliance are the aim. Nowadays, nanocomposites and nanostructured materials are important for several biotherapeutic applications, including their use in drug delivery, in orthopaedics, and in dentistry.