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THE MOLECULAR BIOLOGY OF HYPERSENSITIVITY TO PLANT PATHOGENIC BACTERIA

S. Hutcheson
Published 2001 · Biology

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It has now been nearly 40 years since the first observations by Klement (Klement, 1963) that resistance to bacterial plant pathogens was correlated with a rapid necrotic response induced in artificially inoculated tissue. This response, subsequently termed the hypersensitive response (HR) (Klement et al., 1964), was initially defined as a rapid necrosis observed within 24 h after inoculation of the tissue with a potentially pathogenic, but incompatible, bacterial strain. The response appeared to be part of a syndrome that resulted in localized plant cell death, bacterial localization and bacteriostasis. Two types of incompatible interactions have been identified that are associated with the elicitation of the HR (Klement, 1982). Inoculation of a pathogen of one plant species into another plant species elicited the HR associated with nonhost resistance. The HR could also be elicited when a virulent strain pathogenic to one plant species was introduced into resistant cultivars of that same plant species (race-specific resistance). Although originally controversial, it is now clear that the defense responses associated with hypersensitivity are a primary line of defense to many pathogens, particularly biotrophic pathogens (Goodman and Novacky, 1994; Hutcheson, 1998; Dangl and Jones, 2001; Lam et al., 2001). The response appears to involve protein-mediated recognition of pathogen-derived proteins to initiate several defense responses, including programmed cell death. Cells responding hypersensitively, in turn, signal adjacent cells to accumulate antimicrobial compounds and to initiate the hormonal signaling process associated with systemic acquired resistance. What is most remarkable is that the molecular events occurring during hypersensitivity appear to be very similar to the initiation of innate cellular immunity in mammals and insects (Hutcheson, 1998; Collmer et al., 2000; Staskawicz et al., 2001). Thus, hypersensitivity may represent an ancient form of cellular defense used by eukaryotes in general. For purposes of brevity and simplicity, the discussion below emphasizes the studies on the HR elicited by Pseudomonas syringae strains.
This paper references
10.1073/pnas.92.14.6602
Arabidopsis signal transduction mutant defective in chemically and biologically induced disease resistance.
T. Delaney (1995)
10.1093/emboj/19.15.4004
Direct interaction of resistance gene and avirulence gene products confers rice blast resistance
Y. Jia (2000)
10.1126/science.274.5295.2060
Initiation of Plant Disease Resistance by Physical Interaction of AvrPto and Pto Kinase
Xiaoyan Tang (1996)
10.1094/MPMI-6-553
Nucleotide sequence and properties of the hrmA locus associated with the Pseudomonas syringae pv. syringae 61 hrp gene cluster.
S. Heu (1993)
10.1016/S0092-8674(00)81825-5
Recognition of the Bacterial Avirulence Protein AvrBs3 Occurs inside the Host Plant Cell
G. V. D. Ackerveken (1996)
The Arabidopsis NIM 1 protein shows homology to the mammalian transcriptional factor inhibitor IkB
J Ryals (1997)
European Molecular Biology Organization Journal
10.1128/aem.58.8.2468-2473.1992
Multiple periplasmic catalases in phytopathogenic strains of Pseudomonas syringae.
M. Klotz (1992)
10.1016/0885-5765(90)90091-B
Mechanism of hypersensitive cell collapse: correlation of increased lipoxygenase activity with membrane damage in leaves of Phaseolus vulgaris (L.) inoculated with an avirulent race of Pseudomonas syringae pv. phaseolicola.
K. Croft (1990)
10.1046/J.1365-2958.2000.01870.X
Two novel proteins, PopB, which has functional nuclear localization signals, and PopC, which has a large leucine-rich repeat domain, are secreted through the hrp-secretion apparatus of Ralstonia solanacearum.
M. Gueneron (2000)
10.1128/MMBR.62.2.379-433.1998
Type III Protein Secretion Systems in Bacterial Pathogens of Animals and Plants
C. Hueck (1998)
10.1126/science.8091210
RPS2 of Arabidopsis thaliana: a leucine-rich repeat class of plant disease resistance genes.
A. Bent (1994)
10.1093/oxfordjournals.aob.a085157
The Hypersensitive Reaction and Other Responses of Bean Leaves to Bacteria
Frances M. Lyon (1976)
10.1136/pgmj.68.798.305
Cellular and Molecular Immunology
A. M. Denman (1992)
Varying membrane properties of cells tissues inoculated with HR-inducing bacteria Biotechnology and plant protection: bacterial pathogenesis and disease resistance
A J Novacky (1994)
10.1128/JB.180.8.2244-2247.1998
Erwinia amylovora secretes DspE, a pathogenicity factor and functional AvrE homolog, through the Hrp (type III secretion) pathway.
A. Bogdanove (1998)
10.1126/SCIENCE.284.5418.1322
Type III secretion machines: bacterial devices for protein delivery into host cells.
J. Galán (1999)
10.1128/JB.179.22.7165-7168.1997
Identification of type III secreted products of the Pseudomonas aeruginosa exoenzyme S regulon.
T. Yahr (1997)
10.1016/S0092-8674(00)80083-5
Tomato Prf Is a Member of the Leucine-Rich Repeat Class of Plant Disease Resistance Genes and Lies Embedded within the Pto Kinase Gene Cluster
J. Salmeron (1996)
Attaching and effacing intestinal histopathology and the locus of enterocyte effacement
J. Kaper (1998)
10.1111/j.1365-2958.1994.tb02191.x
Translocation of a hybrid YopE-adenylate cyclase from Yersinia enterocolitica into HeLa cells.
M. Sory (1994)
10.1105/tpc.9.2.209
Localization of hydrogen peroxide accumulation during the hypersensitive reaction of lettuce cells to Pseudomonas syringae pv phaseolicola.
C. Bestwick (1997)
10.1094/MPMI.1998.11.12.1247
Sequences Related to Transposable Elements and Bacteriophages Flank Avirulence Genes of Pseudomonas syringae
J. Kim (1998)
10.1046/J.1365-2958.1999.01165.X
prhJ and hrpG, two new components of the plant signal-dependent regulatory cascade controlled by PrhA in Ralstonia solanacearum.
B. Brito (1999)
10.1073/PNAS.96.11.6523
Interaction of NPR1 with basic leucine zipper protein transcription factors that bind sequences required for salicylic acid induction of the PR-1 gene.
Y. Zhang (1999)
10.1038/29087
Nitric oxide functions as a signal in plant disease resistance
M. Delledonne (1998)
10.1146/annurev.py.09.090171.001423
Current status of the gene-for-gene concept
H. H. Flor (1971)
10.1038/35048500
Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana
A. Theologis (2000)
10.1128/jb.174.6.1734-1741.1992
Organization and environmental regulation of the Pseudomonas syringae pv. syringae 61 hrp cluster.
Y. Xiao (1992)
10.1146/annurev.phyto.33.1.299
Active oxygen in plant pathogenesis.
C. J. Baker (1995)
10.1038/35081184
Programmed cell death, mitochondria and the plant hypersensitive response
Eric Lam (2001)
10.1105/tpc.9.4.641
Inactivation of the flax rust resistance gene M associated with loss of a repeated unit within the leucine-rich repeat coding region.
P. A. Anderson (1997)
The role of the living bacterial cell and induction time in the hypersensitive reaction of the tobacco plant
Z Klement (1967)
10.1094/Phyto-77-1573
Alteration of plasmalemma sucrose transport in Phaseolus vulgaris by Pseudomonas syringae pv. syringae and its association with K+/H+ exchange
M. Atkinson (1987)
10.1128/jb.174.11.3499-3507.1992
Plant and environmental sensory signals control the expression of hrp genes in Pseudomonas syringae pv. phaseolicola.
L. Rahme (1992)
10.1016/S0065-2296(08)60072-5
The Role of Leucine-Rich Repeat Proteins in Plant Defences
David A Jones (1997)
10.1104/pp.110.3.759
The Active Oxygen Response of Cell Suspensions to Incompatible Bacteria Is Not Sufficient to Cause Hypersensitive Cell Death
J. A. Glazener (1996)
10.1128/CMR.11.1.142
Diarrheagenic Escherichia coli
J. Nataro (1998)
10.1016/S1369-5266(00)00080-7
Structure, function and evolution of plant disease resistance genes.
J. Ellis (2000)
Chromosome walking Plant gene isolation: principles and practice
H Leyser (1996)
10.1094/MPMI.2001.14.3.394
Immunocytochemical localization of HrpA and HrpZ supports a role for the Hrp pilus in the transfer of effector proteins from Pseudomonas syringae pv. tomato across the host plant cell wall.
I. Brown (2001)
10.1073/PNAS.040570097
The gene coding for the Hrp pilus structural protein is required for type III secretion of Hrp and Avr proteins in Pseudomonas syringae pv. tomato.
W. Wei (2000)
10.1128/9781555818173.CH3
Pathogenicity Islands and Other Mobile Genetic Elements of Diarrheagenic Escherichia coli
J. Kaper (1999)
10.1016/0092-8674(92)90530-P
Elicitor- and wound-induced oxidative cross-linking of a proline-rich plant cell wall protein: A novel, rapid defense response
D. Bradley (1992)
10.1128/jb.174.6.1875-1882.1992
Expression of Erwinia amylovora hrp genes in response to environmental stimuli.
Z. Wei (1992)
10.1111/j.1365-2958.1995.tb02284.x
The hrp gene locus of Pseudomonas solanacearum, which controls the production of a type III secretion system, encodes eight proteins related to components of the bacterial flagellar biogenesis complex.
F. Van Gijsegem (1995)
Arabidopsis signal
T. Delaney (1995)
10.1105/tpc.8.10.1809
Systemic Acquired Resistance.
J. Ryals (1996)
10.1128/JB.182.17.4711-4718.2000
In vivo and in vitro effects of (p)ppGpp on the sigma(54) promoter Pu of the TOL plasmid of Pseudomonas putida.
M. Carmona (2000)
10.1126/science.8235660
Sensing structural intermediates in bacterial flagellar assembly by export of a negative regulator.
K. T. Hughes (1993)
10.1099/00221287-143-3-693
Avirulence genes in plant-pathogenic bacteria: signals or weapons?
A. Vivian (1997)
10.1105/tpc.12.2.279
The Arabidopsis NPR1/NIM1 Protein Enhances the DNA Binding Activity of a Subgroup of the TGA Family of bZIP Transcription Factors
C. Despres (2000)
10.1046/J.1365-313X.1999.00578.X
A novel myb oncogene homologue in Arabidopsis thaliana related to hypersensitive cell death.
X. Daniel (1999)
10.1038/45471
Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana
X. Lin (1999)
10.1126/science.2781284
Bacterial blight of soybean: regulation of a pathogen gene determining host cultivar specificity.
T. V. Huynh (1989)
10.1094/MPMI-6-515
Characterization of the Pseudomonas syringae pv. syringae 61 hrpJ and hrpI genes: homology of HrpI to a superfamily of proteins associated with protein translocation.
H. C. Huang (1993)
10.1016/S0092-8674(00)00003-9
Apoptotic Pathways Paper Wraps Stone Blunts Scissors
D. Green (2000)
10.1105/tpc.7.9.1357
Disease resistance conferred by expression of a gene encoding H2O2-generating glucose oxidase in transgenic potato plants.
G. Wu (1995)
10.1128/9781555818173
Pathogenicity islands and other mobile virulence elements
J. Hacker (1999)
The Arabidopsis PBS 1 resistance gene encodes a member of a novel protein kinase subfami
M. Swiderski (2001)
10.1128/JB.180.17.4532-4537.1998
Negative regulation of hrp genes in Pseudomonas syringae by HrpV.
G. Preston (1998)
10.1128/iai.61.8.3105-3110.1993
Yops of Yersinia spp. pathogenic for humans.
S. Straley (1993)
10.1094/MPMI-4-081
Isolation of a Gene Cluster fromXanthomonas campestrispv.vesicatoriathat Determines Pathogenicity and the Hypersensitive Response on Pepper and Tomato
U. Bonas (1991)
10.1104/pp.92.1.215
Involvement of plasma membrane calcium influx in bacterial induction of the k/h and hypersensitive responses in tobacco.
M. Atkinson (1990)
10.1016/S0960-9822(02)00510-9
Calcium-mediated apoptosis in a plant hypersensitive disease resistance response
A. Levine (1996)
10.1016/0966-842X(96)81499-5
Sacrifice in the face of foes: pathogen-induced programmed cell death in plants.
R. Mittler (1996)
10.1128/jb.178.12.3462-3469.1996
HrpXv, an AraC-type regulator, activates expression of five of the six loci in the hrp cluster of Xanthomonas campestris pv. vesicatoria.
K. Wengelnik (1996)
10.1094/MPMI-4-415
Current ReviewCellular Coordination of Molecular Responses in Plant Defense
T. Graham (1991)
10.1111/j.1365-2958.1996.tb02615.x
Molecular genetic bases of Salmonella entry into host cells.
J. Galán (1996)
10.1094/Phyto-79-555
O2-Initiated Lipid Peroxidation in a Bacteria-Induced Hypersensitive Reaction in Tobacco Cell Suspensions
L. Keppler (1989)
10.1105/tpc.13.5.1155
Both the Extracellular Leucine-Rich Repeat Domain and the Kinase Activity of FLS2 Are Required for Flagellin Binding and Signaling in Arabidopsis
L. Gómez-Gómez (2001)
10.1016/S1369-5274(99)00045-4
Signaling mechanisms in the antimicrobial host defense of Drosophila.
J. Imler (2000)
10.1126/SCIENCE.1062013
Common and Contrasting Themes of Plant and Animal Diseases
B. Staskawicz (2001)
10.1128/jb.176.4.1025-1036.1994
Identification of a putative alternate sigma factor and characterization of a multicomponent regulatory cascade controlling the expression of Pseudomonas syringae pv. syringae Pss61 hrp and hrmA genes.
Y. Xiao (1994)
10.1094/MPMI-9-0252
Phenotypic expression of Pseudomonas syringae avr genes in E. coli is linked to the activities of the hrp-encoded secretion system.
M. Pirhonen (1996)
10.1146/ANNUREV.IMMUNOL.16.1.225
NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses.
S. Ghosh (1998)
10.1111/J.1439-0434.1999.TB03852.X
Symptomless Resistant Response Instead of the Hypersensitive Reaction in Tobacco Leaves after Infiltration of Heterologous Pathovars of Pseudomonas syringae
Z. Klement (1999)
10.1038/47134
Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana
K. Mayer (1999)
10.1016/0966-842X(96)10039-1
Bacterial entry into epithelial cells: the paradigm of Shigella.
R. Ménard (1996)
10.1128/JB.183.19.5589-5598.2001
Enhancer-binding proteins HrpR and HrpS interact to regulate hrp-encoded type III protein secretion in Pseudomonas syringae strains.
S. Hutcheson (2001)
Diarrheagenic Escherichia coli. Clinical Microbiology Reviews
J P Nataro (1998)
10.1101/087969502.34.785
The Oxidative Burst: Roles in Signal Transduction and Plant Stress
N. Doke (1997)
10.1016/0048-4059(83)90020-6
Generation of superoxide anion by potato tuber protoplasts during the hypersensitive response to hyphal wall components of Phytophthora infestans and specific inhibition of the reaction by suppressors of hypersensitivity
N. Doke (1983)
Characterization of the Pseudomonas syringae pv. syringae Pss61 hrpJ and hrpU operons and analysis of their role in avr gene function
M. C. Lidell (1998)
10.1128/JB.180.19.5211-5217.1998
The Pseudomonas syringae pv. tomato HrpW protein has domains similar to harpins and pectate lyases and can elicit the plant hypersensitive response and bind to pectate.
A. Charkowski (1998)
10.1146/annurev.py.30.090192.000435
Changing Concepts in the Taxonomy of Plant Pathogenic Bacteria
J. Young (1992)
Eukaryotic fatty acid acylation drives plasma membrane targeting and function of several type III effector proteins from Pseudomonas syringae
Z. Nimchuk (2000)
10.1016/0092-8674(94)90544-4
H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response
Alex Levine (1994)
10.1046/J.1365-2958.2001.02271.X
Yersinia YopE is targeted for type III secretion by N-terminal, not mRNA, signals.
S. Lloyd (2001)
10.1172/JCI11837
Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity.
G. Zhang (2001)
10.1094/MPMI-8-0733
The complete hrp gene cluster of Pseudomonas syringae pv. syringae 61 includes two blocks of genes required for harpinPss secretion that are arranged colinearly with Yersinia ysc homologs.
H. C. Huang (1995)
Journal of Plant Pathology
(2001)
10.1016/S0092-8674(00)80470-5
Novel Disease Resistance Specificities Result from Sequence Exchange between Tandemly Repeated Genes at the Cf-4/9Locus of Tomato
M. Parniske (1997)
10.1016/0885-5765(92)90058-4
Early physiological responses associated with race-specific recognition in soybean leaf tissue and cell suspensions treated with Pseudomonas syringae pv. glycinea
E. W. Orlandi (1992)
10.1094/Phyto-64-885
The Quantitative Relation Between Plant and Bacterial Cells Involved in the Hypersensitive Reaction
J. G. Turner (1974)
The syringolide elicitors specified by avirulence gene D and their specific perception by Rpg4 soybean cells
N. T. Keen (1996)
10.1094/MPMI.2000.13.11.1251
Regulation of hrp genes and type III protein secretion in Erwinia amylovora by HrpX/HrpY, a novel two-component system, and HrpS.
Z. Wei (2000)
10.1111/j.1365-2958.1992.tb01764.x
Evidence that the hrpB gene encodes a positive regulator of pathogenicity genes from Pseudomonas solanacearum.
S. Genin (1992)
10.1073/pnas.92.17.7996
Enteropathogenic Escherichia coli contains a putative type III secretion system necessary for the export of proteins involved in attaching and effacing lesion formation.
K. Jarvis (1995)
10.1128/jb.177.21.6201-6210.1995
hrpL activates Erwinia amylovora hrp gene transcription and is a member of the ECF subfamily of sigma factors.
Z. Wei (1995)
10.1073/PNAS.97.16.8770
Pseudomonas syringae Hrp type III secretion system and effector proteins.
A. Collmer (2000)
10.1073/PNAS.96.22.12839
Reciprocal secretion of proteins by the bacterial type III machines of plant and animal pathogens suggests universal recognition of mRNA targeting signals.
D. Anderson (1999)
10.1046/J.1365-2958.1998.01131.X
The type III secretion determinants of the flagellar anti-transcription factor, FlgM, extend from the amino-terminus into the anti-sigma28 domain.
G. S. Chilcott (1998)
10.1128/JB.182.12.3508-3516.2000
The alternative sigma factor RpoN is required for hrp activity in Pseudomonas syringae pv. maculicola and acts at the level of hrpL transcription.
E. L. Hendrickson (2000)
10.1046/J.1365-2958.2001.02455.X
Visualization of secreted Hrp and Avr proteins along the Hrp pilus during type III secretion in Erwinia amylovora and Pseudomonas syringae.
Q. Jin (2001)
10.1046/J.1365-2958.2001.02560.X
Type III secretion in plant growth-promoting Pseudomonas fluorescens SBW25.
G. Preston (2001)
10.1007/978-3-642-78624-2_5
The enigmatic avirulence genes of phytopathogenic bacteria.
J. Dangl (1994)
10.1094/MPMI.2000.13.6.592
A cluster of mutations disrupt the avirulence but not the virulence function of AvrPto.
L. Shan (2000)
10.1016/S0885-5765(88)80017-1
Plasma membrane alteration during bacteria-induced hypersensitive reaction in tobacco suspension cells as monitored by intracellular accumulation of fluorescein
L. Keppler (1988)
Cell contact recognition versus toxin action in induction of bacerial hypersensitive reaction
Z. Klement (1977)
10.1046/j.1462-5822.2000.00056.x
Pathogen‐induced apoptosis of macrophages: a common end for different pathogenic strategies
W. Navarre (2000)
10.1128/MMBR.62.4.1315-1352.1998
The Virulence Plasmid of Yersinia, an Antihost Genome
G. Cornelis (1998)
10.1016/S0966-842X(97)01183-9
'Avirulence genes' in animal pathogens?
J. Galán (1998)
10.1128/JB.183.4.1405-1412.2001
Potential symbiosis-specific genes uncovered by sequencing a 410-kilobase DNA region of the Bradyrhizobium japonicum chromosome.
M. Göttfert (2001)
10.1105/tpc.6.12.1703
Function of Oxidative Cross-Linking of Cell Wall Structural Proteins in Plant Disease Resistance.
L. Brisson (1994)
10.1128/MMBR.64.3.624-653.2000
Bacteria in the Leaf Ecosystem with Emphasis onPseudomonas syringae—a Pathogen, Ice Nucleus, and Epiphyte
S. S. Hirano (2000)
10.1128/jb.175.18.5916-5924.1993
Characterization of the promoter of avirulence gene D from Pseudomonas syringae pv. tomato.
H. Shen (1993)
10.1038/199299b0
Rapid Detection of the Pathogenicity of Phytopathogenic Pseudomonads
Z. Klement (1963)
10.1094/MPMI-8-0444
The avrRpm1 gene of Pseudomonas syringae pv. maculicola is required for virulence on Arabidopsis.
C. Ritter (1995)
Varying membrane properties of cells tissues inoculated with HR-inducing bacteria
A. J. Novacky (1994)
10.1146/annurev.py.28.090190.002053
Working Models of Specific Recognition in Plant-Microbe Interactions
D. W. Gabriel (1990)
10.1016/B978-0-12-509002-5.50018-5
Chapter 9 – Recognition of Bacterial Pathogens by Plants
N. Keen (1982)
10.1126/science.7902614
Map-based cloning of a protein kinase gene conferring disease resistance in tomato.
G. Martin (1993)
10.1128/jb.168.2.512-522.1986
Gene cluster of Pseudomonas syringae pv. "phaseolicola" controls pathogenicity of bean plants and hypersensitivity of nonhost plants.
P. B. Lindgren (1986)
10.1128/jb.176.10.3089-3091.1994
A single promoter sequence recognized by a newly identified alternate sigma factor directs expression of pathogenicity and host range determinants in Pseudomonas syringae.
Y. Xiao (1994)
10.1128/MMBR.64.4.694-708.2000
Coupling of Flagellar Gene Expression to Flagellar Assembly in Salmonella enterica Serovar Typhimurium andEscherichia coli
G. S. Chilcott (2000)
10.1073/pnas.93.26.15497
Molecular recognition of pathogen attack occurs inside of plant cells in plant disease resistance specified by the Arabidopsis genes RPS2 and RPM1.
R. Leister (1996)
The gene coding
W. Wei (2000)
10.1016/0885-5765(89)90013-1
Consequence of O2·− generation during a bacterially induced hypersensitive reaction in tobacco: deterioration of membrane lipids
A. Ádám (1989)
Flagella and motility Escherichia coli and Salmonella: cellular and molecular biology
R M Macnab (1996)
10.1073/PNAS.170128997
Molecular characterization and assembly of the needle complex of the Salmonella typhimurium type III protein secretion system.
T. Kubori (2000)
10.1002/j.1460-2075.1989.tb03508.x
An ice nucleation reporter gene system: identification of inducible pathogenicity genes in Pseudomonas syringae pv. phaseolicola.
P. B. Lindgren (1989)
Hypersensitive reaction induced by phytopathogenic bacteria in the tobacco leaf
Z Klement (1964)
Membrane traffic wardens and protein secretion in gram-negative bacteria.
G. Salmond (1993)
10.1046/j.1365-2958.1996.5731077.x
Unified nomenclature for broadly conserved hrp genes of phytopathogenic bacteria.
A. Bogdanove (1996)
Using the two-hybrid system to detect protein - protein interactions.
P. Bartel (1993)
Flagella and motility
R. Macnab (1996)
10.1146/annurev.phyto.34.1.153
Bacterial avirulence genes.
J. Leach (1996)
10.1094/Phyto-72-1513
Inhibition by Antibacterial Compounds of the Hypersensitive Reaction Induced byPseudomonas pisiin Tobacco
M. Sasser (1982)
10.1094/MPMI-3-112
Bacteria expressing avirulence gene D produce a specific elicitor of the soybean hypersensitive reaction
N. Keen (1990)
10.1126/SCIENCE.278.5345.1963
NDR1, a pathogen-induced component required for Arabidopsis disease resistance.
K. C. Century (1997)
10.1105/tpc.10.2.255
A Plant Homolog of the Neutrophil NADPH Oxidase gp91phox Subunit Gene Encodes a Plasma Membrane Protein with Ca2+ Binding Motifs
T. Keller (1998)
10.1128/9781555818173.CH7
Pathogenicity Islands and the Evolution of Salmonella Virulence
E. Groisman (1999)
10.1128/JB.179.18.5655-5662.1997
The type III (Hrp) secretion pathway of plant pathogenic bacteria: trafficking harpins, Avr proteins, and death.
J. Alfano (1997)
10.1073/PNAS.94.18.9887
A secreted Salmonella protein with homology to an avirulence determinant of plant pathogenic bacteria.
W. Hardt (1997)
10.1126/science.276.5321.2054
Receptor-mediated activation of a MAP kinase in pathogen defense of plants.
W. Ligterink (1997)
10.1094/MPMI.2001.14.2.145
Functional analysis of the type III effectors AvrRpt2 and AvrRpm1 of Pseudomonas syringae with the use of a single-copy genomic integration system.
D. Guttman (2001)
10.1073/pnas.86.1.157
Cloned avirulence genes from the tomato pathogen Pseudomonas syringae pv. tomato confer cultivar specificity on soybean.
D. Kobayashi (1989)
Structure, function and evolution of plant resistance genes
Ellis J Dodds (2000)
A resistance gene product of 168
R T Leister (2000)
10.1094/MPMI-8-0627
Xanthomonas avirulence/pathogenicity gene family encodes functional plant nuclear targeting signals.
Y. Yang (1995)
10.1073/PNAS.011265298
HrpZ(Psph) from the plant pathogen Pseudomonas syringae pv. phaseolicola binds to lipid bilayers and forms an ion-conducting pore in vitro.
J. Lee (2001)
10.1046/J.1365-313X.2000.00744.X
A resistance gene product of the nucleotide binding site -- leucine rich repeats class can form a complex with bacterial avirulence proteins in vivo.
R. Leister (2000)
10.1073/PNAS.97.9.4856
The Pseudomonas syringae Hrp pathogenicity island has a tripartite mosaic structure composed of a cluster of type III secretion genes bounded by exchangeable effector and conserved effector loci that contribute to parasitic fitness and pathogenicity in plants.
J. Alfano (2000)
10.1105/tpc.8.10.1683
Bacterial Pathogens in Plants: Life up against the Wall.
J. Alfano (1996)
Hypersensitive reaction induced by phytopathogenic bacteria in the tobacco
Z. Klement (1964)
The hypersensitive reaction in plants to pathogens: a resistance phenomenon.
R. Goodman (1994)
10.1128/jb.169.2.572-578.1987
Molecular characterization and nucleic acid sequence of an avirulence gene from race 6 of Pseudomonas syringae pv. glycinea.
C. Napoli (1987)
10.1046/J.1365-313X.2001.01014.X
The Arabidopsis PBS1 resistance gene encodes a member of a novel protein kinase subfamily.
M. Swiderski (2001)
10.1128/jb.171.9.5031-5038.1989
The predicted protein product of a pathogenicity locus from Pseudomonas syringae pv. phaseolicola is homologous to a highly conserved domain of several procaryotic regulatory proteins.
C. Grimm (1989)
10.1073/pnas.86.13.4953
Export of an N-terminal fragment of Escherichia coli flagellin by a flagellum-specific pathway.
G. Kuwajima (1989)
10.1007/978-3-642-78624-2_4
hrp genes of phytopathogenic bacteria.
U. Bonas (1994)
The Institute of Genomic Research, and Kazusa DNA Research Institute, 2000. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana
10.1046/J.1365-2958.1999.01403.X
Characterization of the Pseudomonas syringae pv. tomato AvrRpt2 protein: demonstration of secretion and processing during bacterial pathogenesis.
M. B. Mudgett (1999)
10.1093/emboj/19.10.2304
A bacterial sensor of plant cell contact controls the transcriptional induction of Ralstonia solanacearum pathogenicity genes
D. Aldon (2000)
10.1128/jb.174.21.6878-6885.1992
The Pseudomonas syringae pv. syringae 61 hrpH product, an envelope protein required for elicitation of the hypersensitive response in plants.
H. Huang (1992)
10.1105/tpc.8.10.1757
Plant Disease Resistance Genes: Function Meets Structure.
A. Bent (1996)
10.1038/35081161
Plant pathogens and integrated defence responses to infection
J. Dangl (2001)
10.1046/J.0960-7412.2001.01046.X
Eukaryotic features of the Xanthomonas type III effector AvrBs3: protein domains involved in transcriptional activation and the interaction with nuclear import receptors from pepper.
B. Szurek (2001)
10.1073/pnas.92.10.4158
Function of the oxidative burst in hypersensitive disease resistance.
R. Tenhaken (1995)
10.1128/aem.55.7.1724-1729.1989
Influence of Pseudomonas syringae culture conditions on initiation of the hypersensitive response of culture tobacco cells.
I. Yucel (1989)
10.1016/0048-4059(79)90027-4
Evidence that bacterial contact with the plant cell is necessary for the hypersensitive reaction but not the susceptible reaction
R. Stall (1979)
10.1016/S0048-4059(81)80083-5
Inhibition of the hypersensitive reaction of soybean leaves to incompatible Pseudomonas spp. by blasticidin S, streptomycin or elevated temperature
N. Keen (1981)
10.1146/annurev.py.30.090192.002303
Molecular Genetics of Pathogenicity Determinants of Pseudomonas Solanacearum with Special Emphasis on HRP Genes
C. Boucher (1992)
10.1016/0092-8674(93)90354-S
Pseudomonas syringae pv. syringae harpinPss: A protein that is secreted via the hrp pathway and elicits the hypersensitive response in plants
S. He (1993)
10.1146/ANNUREV.PHYTO.36.1.59
Current concepts of active defense in plants.
S. Hutcheson (1998)
10.1073/pnas.94.7.3459
Hrp pilus: an hrp-dependent bacterial surface appendage produced by Pseudomonas syringae pv. tomato DC3000.
E. Roine (1997)
10.1126/science.266.5188.1247
A Central Role of Salicylic Acid in Plant Disease Resistance
T. Delaney (1994)
Hypersensitivity Phytopathogenic prokaryotes
Z Klement (1982)
10.1128/jb.174.6.1742-1749.1992
Phenotypic expression of the Pseudomonas syringae pv. syringae 61 hrp/hrm gene cluster in Escherichia coli MC4100 requires a functional porin.
T. H. Li (1992)
10.1016/0966-842X(93)90087-8
Conservation of secretion pathways for pathogenicity determinants of plant and animal bacteria.
F. Van Gijsegem (1993)
lation of host immune responses , induction of apoptosis and inhibition of NFkB activation by Bordetella type III secretion system
H. YukM. (2000)
10.1073/pnas.93.22.12094
Programmed cell death: a way of life for plants.
J. Greenberg (1996)
10.1016/0952-7915(93)90094-9
Innate immunity.
S. Pillai (1996)
10.1006/JMBI.1998.1643
Structural diversity of leucine-rich repeat proteins.
A. Kajava (1998)
10.1128/9781555818173.CH16
The hrp Cluster of Pseudomonas syringae: aPathogenicity Island Encoding a Type III Protein Translocation Complex?
S. Hutcheson (1999)
10.1128/JB.180.17.4523-4531.1998
Characterization of the hrpC and hrpRS operons of Pseudomonas syringae pathovars syringae, tomato, and glycinea and analysis of the ability of hrpF, hrpG, hrcC, hrpT, and hrpV mutants to elicit the hypersensitive response and disease in plants.
W. Deng (1998)
10.1046/J.1365-2958.1999.01264.X
The alarmone (p)ppGpp mediates physiological-responsive control at the sigma 54-dependent Po promoter.
C. Sze (1999)
10.1094/Phyto-77-1273
Association of host plasma membrane K+/H+ exchange with multiplication of Pseudomonas syringae pv. syringae in Phaseolus vulgaris
M. Atkinson (1987)
Immunobiology Garland
C. Janeway (2001)
10.1038/35081178
Natural products and plant disease resistance
R. Dixon (2001)
10.1111/J.1574-6968.2001.TB10827.X
A putative type III secretion gene cluster is widely distributed in the Burkholderia cepacia complex but absent from genomovar I.
Y. N. Parsons (2001)
10.1094/MPMI.2000.13.12.1312
The Pseudomonas syringae avrRpt2 gene product promotes pathogen virulence from inside plant cells.
Z. Chen (2000)
10.1094/MPMI-4-469
Characterization of the hrp cluster from Pseudomonas syringae pv. syringae 61 and TnphoA tagging of genes encoding exported or membrane-spanning Hrp proteins
H. Huang (1991)
Chromosome walking
H. Leyser (1996)
Function and regulation of Pseudomonas syringae hrp genes
S. W. Hutcheson (1996)
10.1105/tpc.6.11.1583
Characterization of an Arabidopsis Mutant That Is Nonresponsive to Inducers of Systemic Acquired Resistance.
H. Cao (1994)
10.1073/pnas.81.19.6024
Cloned avirulence gene of Pseudomonas syringae pv. glycinea determines race-specific incompatibility on Glycine max (L.) Merr.
B. Staskawicz (1984)
10.1046/J.1365-313X.2000.00804.X
The RPM1 plant disease resistance gene facilitates a rapid and sustained increase in cytosolic calcium that is necessary for the oxidative burst and hypersensitive cell death.
M. Grant (2000)
10.1046/J.1365-2958.2000.01785.X
Modulation of host immune responses, induction of apoptosis and inhibition of NF-kappaB activation by the Bordetella type III secretion system.
M. H. Yuk (2000)
10.1002/j.1460-2075.1995.tb00092.x
Functional conservation of the secretion and translocation machinery for virulence proteins of yersiniae, salmonellae and shigellae.
R. Rosqvist (1995)
10.1046/J.1365-2958.2000.02212.X
Evidence for the secretion of Chlamydia trachomatis CopN by a type III secretion mechanism.
K. Fields (2000)
10.1128/jb.175.15.4859-4869.1993
Molecular analysis of avirulence gene avrRpt2 and identification of a putative regulatory sequence common to all known Pseudomonas syringae avirulence genes.
R. Innes (1993)
10.1016/S1360-1385(01)01893-3
Nitric oxide: comparative synthesis and signaling in animal and plant cells.
D. Wendehenne (2001)
The role of the living bacterial cell and induction time in the hypersensitive reaction of the tobacco
Z. Klement (1967)
10.1128/jb.178.6.1720-1730.1996
Erwinia amylovora secretes harpin via a type III pathway and contains a homolog of yopN of Yersinia spp.
A. Bogdanove (1996)
10.1104/pp.108.2.503
Hrp Mutant of Pseudomonas syringae pv phaseolicola Induces Cell Wall Alterations but Not Membrane Damage Leading to the Hypersensitive Reaction in Lettuce
C. Bestwick (1995)
10.1105/tpc.9.3.425
The Arabidopsis NIM1 protein shows homology to the mammalian transcription factor inhibitor I kappa B.
J. Ryals (1997)
10.1105/tpc.8.7.1095
Expression of the Pseudomonas syringae avirulence protein AvrB in plant cells alleviates its dependence on the hypersensitive response and pathogenicity (Hrp) secretion system in eliciting genotype-specific hypersensitive cell death.
S. Gopalan (1996)
10.1046/j.1365-2958.1996.415946.x
Analysis of the role of the Pseudomonas syringae pv. syringae HrpZ harpin in elicitation of the hypersensitive response in tobacco using functionally non-polar hrpZ deletion mutations, truncated HrpZ fragments, and hrmA mutations.
J. Alfano (1996)
10.1007/978-1-4615-6019-7_7
The hrp-Encoded Protein Export Systems of Pseudomonas syringae and Other Plant Pathogenic Bacteria and Their Role in Pathogenicity
S. Hutcheson (1997)
10.1094/Phyto-75-104
The use of transposon mutagenesis in the isolation of nutritional and virulence mutants in two pathovars of Pseudomonas syringae
D. Anderson (1985)
10.1073/PNAS.95.17.10206
A cloned Erwinia chrysanthemi Hrp (type III protein secretion) system functions in Escherichia coli to deliver Pseudomonas syringae Avr signals to plant cells and to secrete Avr proteins in culture.
J. Ham (1998)
10.1126/SCIENCE.278.5340.1140
A mRNA signal for the type III secretion of Yop proteins by Yersinia enterocolitica.
D. Anderson (1997)
10.1046/J.1365-2958.1998.00920.X
Symbiotic implications of type III protein secretion machinery in Rhizobium.
V. Viprey (1998)
10.1146/annurev.arplant.48.1.575
PLANT DISEASE RESISTANCE GENES.
K. Hammond-Kosack (1997)
Characterization of the hrpJ and hrpU operons of Pseudomonas syringae pv. syringae Pss61: similarity with components of enteric bacteria involved in flagellar biogenesis and demonstration of their role in HarpinPss secretion.
M. Lidell (1994)
10.1094/MPMI-7-0573
Erwinia chrysanthemi hrp genes and their involvement in soft rot pathogenesis and elicitation of the hypersensitive response.
D. W. Bauer (1994)
10.1128/jb.169.12.5789-5794.1987
Molecular characterization of cloned avirulence genes from race 0 and race 1 of Pseudomonas syringae pv. glycinea.
B. Staskawicz (1987)
10.1016/S1369-5274(00)00121-1
A genomic approach to the understanding of Xylella fastidiosa pathogenicity.
M. R. Lambais (2000)
10.1126/science.1621099
Harpin, elicitor of the hypersensitive response produced by the plant pathogen Erwinia amylovora.
Z. Wei (1992)
10.1128/jb.170.10.4748-4756.1988
Molecular cloning of a Pseudomonas syringae pv. syringae gene cluster that enables Pseudomonas fluorescens to elicit the hypersensitive response in tobacco plants.
H. C. Huang (1988)
10.1073/pnas.92.26.11998
Identification of the YopE and YopH domains required for secretion and internalization into the cytosol of macrophages, using the cyaA gene fusion approach.
M. Sory (1995)
10.1046/J.1365-2958.2001.02200.X
Structure and composition of the Shigella flexneri "needle complex", a part of its type III secreton.
A. Blocker (2001)
10.1094/MPMI.1998.11.6.563
The hrpC and hrpN operons of Erwinia chrysanthemi EC16 are flanked by plcA and homologs of hemolysin/adhesin genes and accompanying activator/transporter genes.
J. Kim (1998)
10.1073/PNAS.98.1.373
Negative regulation of defense responses in plants by a conserved MAPKK kinase.
C. Frye (2001)
10.1111/j.1399-3054.1989.tb05625.x
Elicitation of the hypersensitive response by Pseudomonas syringae
S. Hutcheson (1989)
10.1016/0168-9525(94)90105-8
The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats.
M. Mindrinos (1994)
10.1046/J.1365-2958.2000.01851.X
Ralstonia solanacearum produces hrp-dependent pili that are required for PopA secretion but not for attachment of bacteria to plant cells.
F. Van Gijsegem (2000)
10.1128/9781555818173.CH8
The Virulence Plasmid of Shigellae: an Archipelago of Pathogenicity Islands?
C. Parsot (1999)
10.1002/j.1460-2075.1994.tb06341.x
Target cell contact triggers expression and polarized transfer of Yersinia YopE cytotoxin into mammalian cells.
R. Rosqvist (1994)



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